Size control in biology (Record no. 413)

000 -LEADER
fixed length control field 02036nam a2200205Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20230511111529.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170804s2015 xx 000 0 und d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781621820727
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number QP84
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Heald Rebecca
245 ## - TITLE STATEMENT
Title Size control in biology
Remainder of title from Organelles to Organisms
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Cold spring harbor laboratory press
Date of publication, distribution, etc. 2015
Place of publication, distribution, etc. New York
300 ## - Physical Description
Pages: 318p.
490 ## - SERIES STATEMENT
Series statement Cold spring harbor perspectives in biology
520 ## - SUMMARY, ETC.
Summary, etc. Size is a primary feature of living things. From the egg to adult, the various organs, tissues, cells, and subcellular structures that make up an organism achieve appropriate sizes so that they effectively fit and function together. The misregulation of this growth can lead to diseases such as cancer.<br/>Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines our current understanding of the intrinsic and extrinsic mechanisms that precisely regulate the sizes of biological structures so that they can function efficiently in their cellular, organismal, or ecological context. Contributors discuss the genetic, hormonal, and environmental inputs that trigger cells to grow, divide, or die, the various signaling pathways involved, and how these determine the final body size of an organism and the proportions of its component tissues and organs. Size-sensing mechanisms that enable cells to maintain their optimal sizes are reviewed, as are the scaling mechanisms that organelles use to adjust their sizes in response to changes in cell size. Examples from across the tree of life—from bacteria to humans—are provided.<br/>The authors also describe the mysteries that still remain about cell size and its control, including the nature of the intriguing relationship between nuclear DNA content and cell size. This volume will therefore be fascinating reading for all cell, developmental, and evolutionary biologists.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Hariharan, Iswar K.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Wke David B.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Book
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection code Home library Shelving location Date acquired Full call number Accession No. Koha item type
        Physiology ICTS Rack No 14 11/28/2016 QP84 00413 Book